Scientifically studied properties include: anti-inflammatory, antimicrobial, antioxidant, anticancer, diuretic, expectorant, neuroprotective, antidiabetic, hepatoprotective, cardioprotective and radioprotective.
Most modern research into Honeysuckle (Lonicera) focuses on the plant’s anti-inflammatory properties. Honeysuckle may have multiple mechanisms of action, and some findings suggest that its polyphenol content may inhibit pro-inflammatory cytokines. (Those are signaling proteins that initiate the body’s immune system.) This inhibition may be most effective at the beginning of the signaling process. Therefore, Honeysuckle may be better at preventing inflammation than treating it.
A note on inflammation: The body’s immune system response to harmful substances and stimuli is normal and healthy, as it kick-starts the healing process. However, excessive or chronic inflammation can be uncomfortable, prolong illness and lead to additional health complications.
Considerations: As with many herbs, there’s not sufficient evidence that Honeysuckle is safe for pregnant people, breastfeeding individuals and children. Because it may affect blood clotting, people who are on anticoagulants, those who have blood clotting disorders and individuals who are recovering from surgery or planning to have surgery should not use Honeysuckle. Also, Honeysuckle may irritate parts of the digestive tract, so those with colitis, Crohn’s disease, diverticulitis and other intestinal issues should avoid it.
Honeysuckle’s fruit – which is generally spherical and blue, black or red – is toxic and should not be consumed orally.