Scientifically studied properties include: anti-inflammatory, antiviral, analgesic, antipyretic, antimicrobial, antiseptic, anticancer and antioxidant.
Most modern research into Willow Bark (Salix) focuses on its anti-inflammatory properties and use as a pain reliever, particularly among people with osteoarthritis and chronic back pain. Willow Bark’s effectiveness is attributed to salicin, a chemical similar to aspirin that the body uses to make salicylic acid. It’s believed that salicin, as well as other phytochemicals found in Willow Bark, inhibit pro-inflammatory cytokines TNF-alpha and COX-2, signaling proteins that trigger the body’s immune system response. Willow Bark may also interfere with nuclear factor kappa B, a protein involved in gene expression that mediates inflammation.
It’s worth noting that inflammation is not “bad.” It’s a critical part of the body’s protective response to pathogens, viruses, bacteria and other harmful substances and stimuli. Inflammation essentially kickstarts the healing process. However, it can be uncomfortable, and chronic or excessive inflammation can lead to serious health problems and complications.
Considerations: Because it contains salicin, Willow Bark is not safe for those under age 18 due to the risk of Reye’s syndrome, a serious illness associated with aspirin usage. Pregnant and breastfeeding individuals should also avoid Willow Bark.
Willow Bark is contraindicated for people with certain health conditions, including asthma, diabetes, gout and hemophilia. If you have kidney, liver or digestive issues, like gastritis or stomach ulcers, or are allergic to aspirin, you should not take Willow Bark internally.
Willow Bark may interact with some medications, including anticoagulants, nonsteroidal anti-inflammatory drugs (NSAIDs), beta-blockers, diuretics, methotrexate and phenytoin. It may also amplify the effects (and unwanted side effects) of other supplements and herbs.